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  • Leukemia drug shows promise for treating a childhood brain cancer
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    Researchers describe a new use of leukemia drug, nilotinib, to treat a subtype of medulloblastoma, a deadly pediatric brain cancer. ... Read more »
  • New vaccine prevents herpes in mice, guinea pigs
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    A novel vaccine protected almost all mice and guinea pigs exposed to a new herpes virus. This may lead to the vaccine being tested in human studies. ... Read more »
  • Long-acting injectable multi-drug implant shows promise for HIV prevention and treatment
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    UNC researchers have created an injectable multi-drug delivery system that is removable, biodegradable and effective for up to a year in some cases. The author says the ability to administer multiple drugs with this implant is an important advancement in this research. ... Read more »
  • World's first gene therapy for glycogen storage disease produces remarkable results
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    The rare and deadly genetic liver disorder, GSD type Ia, affects children from infancy through adulthood, causing dangerously low blood sugar levels and constant dependence on glucose consumption in the form of cornstarch every few hours for survival. If a cornstarch dose is missed, the disease can lead to seizures... Read more »
  • Malawi study confirms lasting impact of life-saving technology
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    The Malawi Ministry of Health's national adoption of affordable, rugged, neonatal CPAP technology resulted in sustained improvements in the survival of babies with respiratory illness. The three-year study was conducted at 26 Malawi government hospitals that adopted Pumani CPAP devices as a part of routine hospital care between 2013 and... Read more »
  • Why is the brain disturbed by harsh sounds?
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    Neuroscientists have analyzed how people react when they listen to a range of different sounds, the aim being to establish the extent to which repetitive sound frequencies are considered unpleasant. Their results showed that the conventional sound-processing circuit is activated but that the cortical and sub-cortical areas involved in the... Read more »
  • Researchers find way to kill pathogen resistant to antibiotics
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    Researchers have demonstrated a new strategy in fighting antibiotics resistance: the use of artificial haem proteins as a Trojan horse to selectively deliver antimicrobials to target bacteria, enabling their specific and effective sterilization. The technique killed 99.9% of Pseudomonas aeruginosa, a potentially deadly, antibiotic-resistant bacterium present in hospitals. The strategy... Read more »
  • Rethinking how cholesterol is integrated into cells
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    Cholesterol is best known in connection with cardiovascular disease, but cholesterol is also vital for many fundamental processes in the body. Researchers have now presented a completely new, ground-breaking model for the integration and incorporation of cholesterol into cells, with great impact on our understanding of this important process. ... Read more »
  • Dengue virus becoming resistant to vaccines and therapeutics due to mutations in specific protein
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    Researchers have discovered that the dengue virus changes its shape through mutations in Envelope protein to evade vaccines and therapeutics. The study also gives insights on the types of treatment strategies to use at different stages of infection. This could give rise to new approaches in vaccine development and treatment... Read more »
  • Best performance of organic material for lithium battery anode using materials informatics
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    A research group established a new design strategy for organic materials for the anode of lithium-ion secondary cells through the use of Materials Informatics (MI). A high-capacity and high-stability material was successfully obtained via an extremely small number of experiments. ... Read more »

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